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There are two school of thought on this. One says most fungi will be exposed in a two week sterility test. While that may be correct, the operative word is MOST fungi. The other school of thought is that in order to be absolutely sure, one should do a separate fungal test run concurrently with the sterility test. The reasoning is that bacteria prefer a soy based broth in which to grow while fungi much prefer a starcher environment such as a potato dextrose base. We recently had a situation in our lab which proves this point. A client sent in a sample for sterility and fungal testing. The sterility test passed. The fungal test did not demonstrated growth until several days after the sterility test was completed. The tests were repeated using different media lot numbers and the results were the same. Had a separate fungal test not been run, the standard sterility test would not have picked up on the fungal growth. When CSP's are to be invasively introduced into the body, due vigilance has to be the operative word.